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Adenoviral-mediated expression of the MDA-7 gene sensitizes breast carcinoma cells to ionizing radiation

Citrin is expressed variably across tissues, with the liver, kidney, heart, pancreas, and small intestine exhibiting the highest levels [17, 18, 19], whereas aralar (AGC1), a paralog of citrin encoded by SLC25A12 , is primarily expressed in the brain, heart, and skeletal muscle [20]

doi: 10.1111/dom.12049

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Moreover, a continuous feed-back between in silico and in vivo experimentation is necessary for the application of Metabolic Engineering and Systems Biology approaches to living systems [72]