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The PI3K signaling pathway is dysregulated in many tumors, and analyses have shown that PIK3CA is an oncogene that also contributes to tumor progression partially via metabolic reprogramming 188

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Efficacy of oral folinic acid supplementation in children with autism spectrum disorder: a randomized double-blind, placebo-controlled trial

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Fe 3+ subsequently binds to transferrin (TF) or lactoferrin (LF) to form a TFFe 3+ complex, which is then recognized and internalized by transferrin receptor 1 (TFR1) on the cell surface (Zhao et al., 2025b)