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Assays of stroma and thylakoid fractions showed no detectable GCL and GS activity in the lumen (unpublished data)

This insulin deficiency may cause substantial lipolysis in adipose tissue, releasing large amounts of fatty acids that, if not efficiently utilized, could impair cellular functions

An animal study in a reserpine-induced fibromyalgia rat model found that nano-pregabalin (N-PG) alleviated FM symptoms by enhancing CNS penetration, restoring neurotransmitter balance (Glut, NE, CGRP), increasing antioxidant enzyme activity (e.g., SOD), inhibiting pro-inflammatory transcription factors (e.g., NF-B), and reducing apoptosis by decreasing caspase-3 (Casp-3) activation (36)

Financial Overview 11.3.8.4

Metabolic reprogramming, as one of the characteristics of cancer, gives cancer cells the potential to grow and proliferate in the nutrient-deficient TME [34, 35]