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Notably, some metabolites, such as ligustilide, have been clinically applied in the treatment of CCVDs ( This study conducted a systematic literature search using keywords such as Chuanxiong, traditional Chinese medicine, chemical components, metabolites, CCVDs, and pharmacological effects

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Atherosclerosis 130 , 2936 (1997)

Alcohol consumption can impact the occurrence and progression of alcohol-associated liver disease (ALD) by modulating immune cells and immune-related cells such as macrophages, neutrophils, hepatic stellate cell (HSCs), T lymphocytes, natural killer T (NKT) cells, and liver sinusoidal endothelial cells (LSECs) through epigenetic modifications (DNA methylation, histone modifications, microRNA, RNA methylation)