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Physical changes like pale skin or a sore tongue, and digestive issues such as loss of appetite or constipation, may also be signs your body needs more B12

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doi: 10.1210/jc.2010-1587 77 Johns Hopkins University

In the DRIVE-SHIFT clinical trial of virologically suppressed adults who switched to once-daily DOR/3TC/TDF, slight weight gain consistent with the weight gain expected in people without HIV was observed although approximately 40% of individuals lost weight or had no change in weight through 144 weeks [20]