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Nature 210 (5035), 540541 (1966) H.W

doi: 10.1038/s41418-021-00841-9 6 ChaudhrySHaroonFIrfan WaheedKAVictorGShahzadMFatimaB

On the contrary, treatment with Miln and Van led to 2.36- and 2.4-fold elevations in TCF compared to the FM group, respectively

Because CD4 + T-cell activation and T helper cells differentiation are highly dependent on aerobic glycolysis, inhibition of autoreactive T-cell activation and T helper cells differentiation by targeting glycolysis or ROS generation without damaging systemic immune function is a promising direction for solving the problems of current treatment options