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Resident alveolar macrophages are master regulators of arrested alveolarization in experimental bronchopulmonary dysplasia

doi: 10.1073/pnas.2405474121 [DOI] [PMC free article] [PubMed] [Google Scholar] 118

However, clinical trials assessing the efficacy of these techniques exclude the majority of the patient population with red knees, patients with large lesion size, high mechanical demands, older age, inflammation, infection, and other systemic diseases

Since DFO was first discovered to have an inhibitory effect on ferroptosis caused by erastin and RSL3, DFO is the drug most widely used to inhibit lipid peroxidation-mediated ferroptosis under various conditions ( in vivo and in vitro ( Deferasirox Deferasirox is a membrane-permeable iron chelator and the first oral medication approved by the Food and Drug Administration (FDA) for chronic iron overload in the body caused by multiple blood transfusions