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A terminally differentiated epithelial cell can turn into a progenitor/stem cell, which can produce a new lineage of cells to replace the missing cells in the airway epithelium under normal homeostatic conditions and can maintain its numerical stability in the airway epithelium by self-renewal, which can lead to wound healing and tissue regeneration (75)

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In contrast, patients with early-stage steatosis or those embedded in a context of profound systemic insulin resistance may present a less amenable target for short-term LC monotherapy, as the driving pathophysiology extends beyond immediate fatty acid flux

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