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Gene discovery in amyotrophic lateral sclerosis: implications for clinical management

In the SIMGI model (an in vitro simulator of human digestion), a single dose of 0.166 g of PLAa widely used biodegradable plastic was followed by 72-h colonic fermentation

Furthermore, propionic acid stimulates enteric neurons to release glutamate, which activates vagal afferents to transmit signals to the CNS, modulating mood-related brain circuits ( Foundation for SCFA production: dietary fiber (especially fructans and galactooligosaccharides) can significantly increase the abundance of Bifidobacterium and Lactobacillus in the gut (124), and these two bacterial groups are the main producers of SCFAs (100102)

Amin et al

Using transcriptome data from AA patients and controls from datasets GSE68801 and GSE80342, we aimed to identify AA diagnostic marker genes linked to ferroptosis