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Resistant lines have increased replication relative to wild type RH parasites in competition assays carried out in the presence of auranofin

GSH has a free electron it can donate to reactive oxygen species, such as free radicals, to neutralize them, thus preventing them from damaging cells

By gross examination of FRDA and control postmortem brains using Perls Prussian blue stain which detects labile iron, Koeppen et al

That is why the in-clinic options are more effective

It would be useful if the genotype and peripheral blood film of this infant were available, as these may provide some insights on the in vivo clearance or the existence of these Heinz bodies