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doi: 10.1016/j.cellsig.2023.111006 164 QianZZhangQLiPLiYZhangYLiRet al

However, the current available antibody assay has low sensitivity and studies have found that antibodies are only detectable in 4060% of pernicious anaemia cases, so a negative test cannot categorically exclude pernicious anaemia[18,19]

Approximately 0.1-0.2% of the body's total B12 stores are lost daily through urinary and faecal excretion , representing a relatively slow depletion rate compared to other water-soluble vitamins

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