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Pregnant Women : The need for B12 increases during pregnancy, especially for those on plant-based diets

### Alternative: 2.5mg/mL (Better for Low Doses) | Vial Size | BAC Water to Add | Concentration | Volume per 0.5mg Dose | |-----------|-----------------|---------------|-----------------------| | 5mg | 2.0mL | 2.5mg/mL | 0.20mL | | 10mg | 4.0mL | 2.5mg/mL | 0.20mL | This lower concentration produces larger injection volumes easier to measure precisely, but more volume per shot

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Vitamin B12 is given intravenously to treat cyanide poisoning

A 2025 meta-analysis pooling three trials (878 participants) confirmed the pattern: significantly greater weight loss than placebo about ~14% of total body weight on average with no significant rise in overall adverse events [6] [7]