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Plant J 2:12931 Creissen GP, Mullineaux PM (1995) Cloning and characterization of glutathione reductase cDNAs and identification of two genes encoding the tobacco enzyme

Increases above normal ranges should prompt evaluation

Given that tumor cells exhibit elevated ROS levels due to accelerated metabolic and proliferative activity, ferroptosisa process intimately linked to redox imbalancemay offer a targeted therapeutic approach for MM and other cancers (Figure 3)