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A further small study done recently on 10 paediatric patients similarly found that intranasal OH-Cbl normalised serum B12 levels in deficient patients ( Subcutaneous B12 Subcutaneous B12 is occasionally used, especially in patients with inborn errors of cobalamin metabolism, who need high pharmacological doses of B12 to maintain their B12-dependent metabolic pathways and related biochemistry within normal range

This involves lowering blood glucose levels with insulin and taking blood tests to measure the response to this stress

In general, keep oral supplements in a cool, dry place away from direct heat, moisture, and sunlight

17, Supplementary Tables 1 and 2 and Supporting immunoblots for Supplementary Figs