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This argument was supported by the combination of BCAT 1 inhibitor and -KG induced tumor cell death in patient-derived IDH WT GBM

Day 1: S1 + 3 M CHIR99021 (Peprotech, USA) + 100 ng/mL Activin A (Peprotech, USA) + 250 M vitamin C (Sigma Aldrich, USA)

RNA-seq reveals IMP-induced overexpression of AHR and ALDH3A1 signaling in lung epithelial cells To clarify the potential mechanisms underlying IMPs protective effects on LPS-induced lung epithelial cells, transcriptome sequencing was performed on both control A549 cells and 20 M IMP-treated cells (Fig

Shih AY, Murphy TH