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The substrates of this alteration are directed to the polyol pathway, which, at normal glucose concentrations, is not active [38]

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Similar content being viewed by others Introduction Neurodevelopmental disorders (NDDs) are a group of neuropsychiatric conditions resulting from developmental impairments in the central nervous system

As per the latest diagnostic criteria, MetS necessitates the presence of any three out of the following five conditions: elevated fasting glucose or type 2 diabetes (T2D), hypertriglyceridemia, lowered high-density lipoprotein (HDL) cholesterol levels, central obesity, or hypertension (Alberti et al., 2009)