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A small pilot study in athletes found more consistent blood levels when oral doses were taken in a fasted state versus with dinner in the evening

Biochem Biophys Res Commun 733:150597

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Established research on intranasal peptide delivery exists for oxytocin, insulin, and several neuropeptides

Compound 4 (1.94 g, 2.47 mmol), H-Lys-OMe2HCl (0.24 g, 1.03 mmol), PYBOP (1.62 g, 3.10 mmol) and HOBT (0.42 g, 3.10 mmol) were dissolved in DMF (40 mL) under nitrogen atmosphere and ice bath conditions