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Despite its efficacy, particularly in younger animals, ASTs neuroprotective effects appear to diminish with age, highlighting the need for further research to optimize its therapeutic potential

Bock M, Karber M, Kuhn H

Additionally, activated STING play a role in promoting NF-B/I-B activation, which further contributes to STING pathway activation and exacerbates ROS-induced oxidative DNA damage [152]