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Therefore, we aimed to explore the role of GPX4 in Raji cells

NRF2 is reported to have suppressive effects on the lipogenic pathway via inhibiting the activity of LXR 64,70 , a transcription factor that supports lipid synthesis

Sirtuin-3 can also rescue kidney function by relieving mitochondrial oxidative stress ( 3.2.2.1 Curcumin Curcumin, the bioactive compound extracted from turmeric , shows the potent therapeutic effects in various diseases including renal IRI, shock and myocardial ischemia with its antioxidant properties (Trujillo et al., 2013)