glutathione synthetase deficiency smear Nineteen-year follow-up of a patient

Nineteen year follow up of a patient with severe glutathione synthetase deficiency Journal of Human Genetics When red blood cells grow irregular spikes, the smear may be pointing toward membrane lipid damage: ACANTHOCYTES (SPUR CELLS). In hematology, acanthocytes are red blood cells with irregularly spaced, uneven, pointed Inclusion Bodies of Red Blood Cells The Art Of Medicine #imageoftheday, A 24 year old man develops acute jaundice and dark urine after starting trimethoprim sulfamethoxazole. A peripheral smear reveals the specific cellular defects shown. The underlying Impaired Glutathione Synthesis in Neurodegeneration

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