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Oral administration of deferiprone, an iron chelator, enhances IEC repair and alleviates clinical symptoms in patients with IBD [64]

The release of DAMPs is conducive to augmenting the immune response activation

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doi: 10.3389/fpls.2013.00314 Received 30 May 2013 Accepted 26 July 2013 Published 16 August 2013 Volume 4 - 2013 Edited by Emmanuel Baudouin, Universit Pierre et Marie Curie - Paris 6, France Reviewed by Vasileios Fotopoulos, Cyprus University of Technology, Cyprus

IGF-1 LR3 primarily exerts its effects through activation of the IGF-1 receptor (IGF-1R), a transmembrane tyrosine kinase receptor expressed in muscle, bone, connective tissue, and various other cell types