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Numerous studies have demonstrated that HO-1 has a significant effect on diabetic complications, with induction of HO-1 protein expression enhancing antioxidant defense and reducing inflammatory factors (Table 2)

This is a preview of subscription content, access via your institution Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription $32.99 / 30 days cancel any time Subscribe to this journal Receive 12 print issues and online access $259.00 per year only $21.58 per issue Rent or buy this article Prices vary by article type from$1.95 to$39.95 Prices may be subject to local taxes which are calculated during checkout References Boehncke, W