immunocal clinical trial glutathione randomized Pack of 2 (1 Regular and 1 Platinum) – Precursor – Sante Medi A Cystine‐Rich Whey Supplement (Immunocal®)

Ferroptosis have been demonstrated to trigger and amplify the inflammatory responses [21, 39,40,41]

Lambs 0.5mL at tailing or weaning Sheep1 - 1.5mL pre-lambing Calves 2 - 3mL from 2 months of age Cows 4 - 6mL pre-calving DO NOT dose within 3 months of the previous dose Do Not exceed stated dose Cobalt deficiency in soil and/or pasture leads to a lack of Vitamin B12 in body tissues of stock which, subsequently, may have poor growth rates and ill thrift, particularly in young animals Before treatment, establish selenium status of stock, pasture cobalt levels and/or Vitamin B12 status of stock Do not use this product unless animals are deficient in both cobalt and selenium Treatment is likely to last only 4-6 weeks if liver storage levels of Vitamin B12 and pasture levels of cobalt are low Treatment of pregnant ruminants should benefit newborn animals, particularly when treated in latter stages of pregnancy Supplementation of young ruminants should begin at or before weaning Do not redose with this product within three months of the previous dose

10.1016/j.neubiorev.2013.11.009 41

Reported or plausible effects can include local irritation, redness, swelling, or discomfort at the application or injection site, as well as headache, nausea, dizziness, flushing, or fatigue

RMD Open 7:e001735