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However, existing in vitro BBB models cannot mimic these dynamic pathological changes and spatial heterogeneity, leading to fundamental limitations in predicting drug permeability and the therapeutic window

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Gastrointestinal symptoms such as loss of appetite, constipation, or diarrhoea may also occur, though these are non-specific and can have many causes

Treatment Options for B12 Deficiency Treatment for vitamin B12 deficiency varies depending on its severity and underlying cause

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