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Simple cryosurgical treatment of the oral melanotic macule ScienceDirect Dark Spot on Lip: Harmless or Serious? What to Check First This is a 755nm alexandrite picosecond laser treatment of labial melanotic macules on the gingiva. She has many more of these benign pigmented spots on her lips. They are safely, selectively, and Happy Wednesday! In this video, a patient's labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules' are flat and asymmetrical with a tan brown to black Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome

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