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Evaluation of modulatory effects of saffron (Crocus sativus L.) aqueous extract on oxidative stress in ischemic stroke patients: a randomized clinical trial

JM109 competent cells (Promega, Madison, WI, USA) were transformed with the ligation reaction

They significantly decrease markers of oxidative stress (ROS, NO) and inflammation ( TNF- , IL-1 ), while modulating pathways involved in lipid metabolism ( PPAR- ) and antioxidant defense ( HO-1 , Nrf2 ), with the latter extract specifically shown to suppress the TLR4/MyD88/NF-B signaling pathway (Xiong et al., 2019

This research supports the idea that seaweed can act as a functional ingredient to boost digestive efficiency and energy metabolism in dogs, which ties into hormonal health by aiding weight management and nutrient uptake