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all tests were two-tailed and = 0.05 for each analysis

The proportion of participants achieving 20% or greater weight loss was 36% at the 10mg dose and 40% at the 15mg dose, results approaching what was previously achievable only with bariatric surgery

In that sense, if 5-amino-1MQ had effects on the same molecular pathways as exercise, aged mice treated with the compound that also exercised would not receive much of an effect from the treatment