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Individuals with absorption issues, such as those with gastrointestinal disorders or certain genetic conditions, may not benefit from oral supplements

Limits of the workup A B12 value alone neither confirms nor excludes malignancy, and clinical judgment decides whether to observe, repeat, evaluate further, or refer

Those with poor circulation in the lower extremities (peripheral vascular disease) may experience altered absorption rates

Doi:10.1210/jc.2006-1702 The information in this article is intended for educational use only and shouldn't be considered medical advice