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And in the field of fat grafting, ADSCs significantly improve the survival rate of transplanted fat by suppressing inflammation, reducing ROS, and promoting angiogenesis through interactions between the Nrf2 and TLR4/NF-B pathways, highlighting their potential application in regenerative medicine [115]

It is not naturally produced in the body and is primarily found in supplements

Interference with the Trx system with siRNA or inhibitors significantly inhibits tumor cell growth, suggesting the Trx system is crucial to tumor growth

The pharmacokinetic and biopharmaceutical features of exogenous antioxidants and their ability to cross BBB to reach tumor sites should also be considered to achieve the desired therapeutic effect in brain cancer treatment