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(1/) pnas.org/doi/abs/10.107 Females show higher mtROS levels and insufficient antioxidant levels, while males show mitochondrial lipid oxidative damage

For some researchers, the additional weight loss from higher doses is not worth the increased side effect burden, and a dose between 1.0 and 1.7 mg represents their personal optimal balance

Altogether the findings of this study indicate that it is possible to replace one or two doses of mesna with ternatin with a positive outcome in terms of prevention of hemorrhagic cystitis thus indicating that ternatin can indeed be therapeutically likely used in the treatment of the condition in question

PLoS One 10(6):e0131038

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