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Generation of expression constructs For the generation of hpaA expression constructs, hpaA and derivatives were amplified by PCR from X

A premature or spontaneous acrosome reaction makes the spermatozoa incompetent to interact with the oocyte and thereby to impair its fertilisation rate 70

Co-stimulatory or co-inhibitory signals pathway, immune checkpoints, and the presence of specialized cell populations form the basis of peripheral tolerance, which are determinants for modulating the immune response [30,31,32]

and (iii) activation of signaling pathways including p38 mitogen-activated protein kinase, epidermal growth factor receptor, Rho GTPase, MYC proto-oncogene, MEK 1/2, and caspases

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