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2 Materials and methods 2.1 Mice All the animal experiments were approved by the Experimental Animal Ethics Committee of Guangdong Pharmaceutical University and adhered to the ARRIVE guidelines

Nanomaterials (Basel, Switzerland)

Pharmacological blockade using MRS2179, an antagonist of the P2Y1 receptor, restores synaptic balance and may represent a promising strategy for treating drug-resistant epilepsy [424, 425]

Establish a baseline before beginning the medication and track any changes in the weeks or months following

It can be quite a painful trial for many a condition not only comes with physical discomfort but also a lot of mental anxiety about ones appearance