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Crombie' group from American and Hong' group from Korea re-designed the benzenesulfonamido aminopyrimidine scaffold through the introduction of other substituent groups at R 1 , respectively, and got two representative inhibitors 66 and 67 that possessed a low nanomole level of inhibitory potentials [178, 179]

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Biochemical characterization of glutaredoxins from Chlamydomonas reinhardtii reveals the unique properties of a chloroplastic CGFS-type glutaredoxin