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More recently, non-canonical roles of LDHA and LDHB have been identified, with both isoforms contributing to ferroptosis resistance in IRI and cancer through mechanisms associated with GPX4 activity or GSH availability (48,49)

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Early studies suggest that common side effects may include gastrointestinal symptoms such as nausea, vomiting, and diarrheaside effects that are generally associated with peptide-based therapies