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There is a significant age-dependent increase in ferroptosis in the kidney, spleen, liver, ovary, uterus, cerebellum, and bone marrow, accompanied by iron accumulation 41

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This reduction results in diminished intestinal REG3G (Regenerating Family Member 3 Gamma) expression and increased bacterial translocation to the liver, exacerbating liver inflammation [152]

Do not apply to parts of the skin that have rashes, are cut, or are infected

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