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10.3171/2009.2.JNS081199

10.1016/j.bej.2010.01.011 26 Garcia-OrtegaX.AdelantadoN.FerrerP.MontesinosJ

The discovery of its biological activity came from an unexpected observation: serum from young donors (age 20-25) could stimulate aged liver tissue to synthesize proteins at a rate characteristic of younger tissue, while serum from older donors (age 60-80) could not

A Venn diagram was used to display the protein abundance patterns, highlighting the upregulated and downregulated DAPs for thorough understanding (Fig