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Description

B12 deficiency can lead to severe and potentially irreversible neurological damage if misdiagnosed or inadequately treated

Additionally, rectal administration can result in higher bioavailability and faster onset of action compared to some other routes, as the medication bypasses the first-pass metabolism in the liver

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Perhaps the most important methodological details involve time and temperature

Its primary mechanism centres on enhancing tissue oxygenation, an indispensable component of cellular metabolism, by augmenting oxygen delivery to hypoxic tissues, thereby fostering optimal conditions for metabolic and repair processes [20, 26, 32]