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Other antiretroviral classes, including non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (PIs), do not directly inhibit Pol- but are still associated with mitochondrial dysfunction through alternative mechanisms (107, 108)

While we provide functional context for several loci identified in this study, including TUT4 , RYK , MOXD1 , UBAP2 , GATA5 , and others, we acknowledge that many of these interpretations rely on indirect evidence from related biological pathways or associations with non-ocular traits such as age-related macular degeneration, cardiovascular traits, or metabolic phenotypes

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Skin Aging Alpha-lipoic acid has been promoted for improving the appearance of aging skin, but there is no clinical evidence that oral alpha-lipoic acid supplements have such an effect [1]

By including ALA in a supplement routine, individuals can improve skin clarity, support collagen production, and enhance the overall effectiveness of their melanin reduction efforts