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Interestingly, glutamine was inversely associated with blood pressure in human subjects without diabetes mellitus or cardiovascular disease [27]

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Moreover, SIRT1 levels were increased directly in the NAc by the use of viral-mediated gene transfer, which resulted in an increase in depressive- and anxiety-like behaviors when mice were assessed in the open-field, elevated plus maze, and forced swim tests

Images were acquired by fluorescence microscopy (IX61, Olympus, Japan)

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