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In the HS model, both protein misfolding and excessive production of reactive oxidative species (ROS) can stimulate this stress response [50, 51]

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According to the previous study, CAT deficiency was associated with an increase in adipose tissue and increased levels of serum TG, suggesting a crucial role for catalase in lipid mobilization (25)

Hepatic Impairment and Liver Disease Hepatic impairment reduces escitalopram oral clearance by 37% and approximately doubles the elimination half-life, per FDA pharmacokinetic data