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Other advances have been realized by rational optimization of bNAb epitopes, resulting in increases in the breadth and potency of NAb responses elicited after immunization 23

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Biol Pharm Bull 25:945953 Nakanishi S, Nakajima Y, Masu M, Ueda Y, Nakahara K, Watanabe D, Yamaguchi S, Kawabata S, Okada M (1998) Glutamate receptors: brain function and signal transduction