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Rev Bras Farmacogn 24:468480 Bai H, Li H, Zhang W, Matkowskyj KA, Liao J, Srivastava SK, Yang G-Y (2011) Inhibition of chronic pancreatitis and pancreatic intraepithelial neoplasia (panin) by capsaicin in lsl-kras g12d/pdx1-cre mice

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This review summarizes the current understanding of the molecular mechanisms underlying APAP-induced liver injury, introduces how fructose supplementation could prevent and treat APAP liver toxicity with a focus on the ChREBP-FGF21 pathway, and proposes possible future directions of study