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Level of Evidence IV This journal requires that authors assign a level of evidence to each article

M.de BoerR

Birth control, some anti-convulsant or seizure meds, antibiotics, and Metformin can decrease B12 levels

Now, as Ive said, this isnt unexpected

In a rat model simulating tyrosinemia type II through chronic L-tyrosine administration, NAC co-treatment effectively prevented the decline in ChAT activity in the cerebral cortex and partially reversed the increase in AChE activity in the hippocampus and striatum [120]