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10.1038/nsmb.3194 Nat

D.SartorR

Key challenges include: Multiple underlying causes Complex nerve repair processes Varied symptom presentations Individual response differences Limited nerve regeneration ability Ongoing damage in some cases The Complex Nature of Nerve Damage Understanding nerve damage helps explain why finding a cure is so challenging

Normal is not the same as optimal

Nevertheless, all tested potential NUPR1-regulated targets were modulated as predicted by IPA in our culture system except for CEP170B, which confirms them as NUPR1-dependent targets also in human bronchial epithelial cells