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Although in vitro studies indicated that DEXILANT has the potential to inhibit CYP2C19 in vivo, an in vivo drugdrug interaction study in mainly CYP2C19 extensive and intermediate metabolizers has shown that DEXILANT does not affect the pharmacokinetics of diazepam (CYP2C19 substrate)

Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice

Hydrogen sulfide-linked sulfhydration of NF-B mediates its antiapoptotic actions

33 , 10011012.e1005 (2021)

doi: 10.1016/j.redox.2015.07.012 248 SchurinkB.RoosE.RadonicT.BarbeE.BoumanC