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It can be given with IV hydration or as a vitamin B12 shot

doi: 10.1080/10826084.2019.1691597 17 Dogan-SanderE.KohlsE.BaldofskiS.Rummel-KlugeC

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CrossRef Correlation of Cystatin C- and Creatinine-Based Renal Equations With Lipid Parameters in Chronic Kidney Disease: A Case-Control Study Smita H Vasava, Roshni G Sadaria, Devanshi P Gosai Cureus.2026;[Epub] CrossRef Impact of remnant cholesterol on short-term and long-term prognosis in patients with prediabetes or diabetes undergoing coronary artery bypass grafting: a large-scale cohort study Zhongchen Li, Chunyu Yu, Heng Zhang, Runze Chen, Yan Zhao, Zhe Zheng Cardiovascular Diabetology.2025;[Epub] CrossRef Effects of Tocotrienol on Cardiovascular Risk Markers in Patients With Chronic Kidney Disease: A Randomized Controlled Trial Liana Trugilho, Lvia Alvarenga, Ludmila Cardozo, Bruna Paiva, Jessyca Brito, Isis Barboza, Jonatas Almeida, Juliana dos Anjos, Pramod Khosla, Marcelo Ribeiro-Alves, Denise Mafra, Eric Gumpricht Journal of Nutrition and Metabolism.2025;[Epub] CrossRef The Impact of Glomerular Disease on Dyslipidemia in Pediatric Patients Treated with Dialysis Edward Zitnik, Elani Streja, Marciana Laster Nutrients.2025

The importance of these pathways in yielding pyruvate in the absence of pyruvate kinase is further supported by many reports showing that inhibition of this enzyme does not lead to a proportional decrease in pyruvate/lactate formation, reviewed in ref