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Description

10.3389/fcell.2021.649045 Front

Shearer, W

The level of superoxide anion radicals increased in proportion to the DMSO concentration, but in sod mutant cells this effect was much stronger

Another consideration is compatibility

This lively debate underscores the importance of accurate parameters when extrapolating in vitro enzyme data: the two hypotheses are not mutually exclusive, but remind us that we must directly and precisely quantify substrate concentrations in the mitochondrial matrix when constructing physiological models