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Reversible Facial Hyperpigmentation Associated With Vitamin B12 Deficiency Tayem 2017 Nutrition in Clinical Practice Wiley Online Library Acquired hyperpigmentation, often on the hands and feet, can be a sign of vitamin B12 deficiency. It is reversible once the B12 deficiency is corrected. Keep in mind, this isn't the only Knuckle Pigmentation as an Early Cutaneous Sign of Vitamin B12 Deficiency: A Case Report PMC Reversible Hyperpigmentation due to Vitamin B12 Deficiency Mimicking Addison's Pigmentation Indian Journal of Postgraduate Dermatology Those White Spots on Your Arm Could Be a Sign of a Vitamin B12 Deficiency

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