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Chromium picolinate (at a dose of 200 g/day) combined with carnitine (1000 g/day) in women with polycystic ovary syndrome for 12 weeks showed a significant improvement of stress, depression, and anxiety [113]

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For instance, human plasma-derived exosomes suppress hippocampal neuronal apoptosis and enhance spatial learning and memory in MMAemia mice, primarily through their cargo miRNAs (e.g., miR-9, miR-199a) that regulate apoptosis-related pathways (Zhou et al

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