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[133] Human trials with dosages as high as 140 mg/kg NAC were unable to show any prevention of cardiomyopathy due to treatment with doxorubicin

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A second larger expansion of GS-like genes (Clade 3) was present in the last common ancestor of the syncytia-forming cyst and reniform nematodes, which both lie on one side of a major bifurcation in the evolution of plant-sedentary endoparasitism (Fig 1)